Article
Wild type p53 reduces the size of tumors caused by bovine leukemia virus-infected cells.
Cancer letters - 19 Mar 1996
Dees C, Godfrey V L, Schultz R D, Travis C C
Abstract excerpt
Bat lung (BAT(2)CL6) cells infected with bovine leukemia virus (BLV) cause malignant tumors in nude mice that after 6 weeks subcutaneous growth, have an average volume of 0.3m(3). Uninfected bat lung cells (Tb 1 Lu) produce small benign neoplasms that average 0.003 cm(3). BAT(2)CL6 cells were transfected in vitro with expression vectors that produce wild type human or mutant p53. Production of human p53 in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
