Wild-type p53 induces apoptosis in a Burkitt lymphoma (BL) line that carries mutant p53.

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Article

Wild-type p53 induces apoptosis in a Burkitt lymphoma (BL) line that carries mutant p53.

Oncogene - 1 Jun 1993

Ramqvist T, Magnusson K P, Wang Y, Szekely L, Klein G, Wiman K G

Abstract excerpt

All Burkitt lymphoma (BL) biopsies and cell lines carry a c-myc/Ig translocation. The resulting constitutive activation of c-myc is regarded as an essential factor for the progressive growth of the tumor cells. At least 60% of BL cell lines carry a mutated p53 gene as well. It has been shown that...

Topics

Apoptosis
Base Sequence
Biopsy
Burkitt Lymphoma
Cell Division
Chromosomes, Human, Pair 14
Chromosomes, Human, Pair 8
DNA, Neoplasm
Genes, Immunoglobulin
Genes, myc
Genes, p53
Humans
Immunoglobulin Heavy Chains
Kinetics
Molecular Sequence Data
Mutation
Oligodeoxyribonucleotides
Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 8502475

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8502475-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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