Article
Function and conformation of wild-type p53 protein are influenced by mutations in bovine leukemia virus-induced B-cell lymphosarcoma.
Virology - 30 Mar 1998
Tajima S, Zhuang W Z, Kato M V, Okada K, Ikawa Y, Aida Y
Abstract excerpt
The mutations of the p53 gene previously represented one of several genetic changes involved in the development of bovine leukemia virus (BLV)-induced lymphosarcoma, while the effects of these mutations on the function of p53 are unknown. We identified four mutations of p53 gene in BLV-infected c...
Topics
- Animals
- Cattle
- Gene Expression Regulation, Neoplastic
- Gene Expression Regulation, Viral
- Genes, Viral
- Humans
- Lymphoma, Non-Hodgkin
- Mutation
- Protein Conformation
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53
