Article
Predominant p53 mutations in enzootic bovine leukemic cell lines.
Veterinary immunology and immunopathology - 15 Jun 1996
Komori H, Ishiguro N, Horiuchi M, Shinagawa M, Aida Y
Abstract excerpt
The role of the p53 tumor suppressor gene in bovine lymphosarcomas, a fragment of about 100 bp corresponding to approximately 97% of the open reading frame of the p53 gene was first amplified from single-strand cDNA originated from calf thymus by polymerase chain reaction PCR) and sequenced to ob...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Southern
- Cattle
- Enzootic Bovine Leukosis
- Genes, p53
- Immunophenotyping
- Leukemia Virus, Bovine
- Molecular Sequence Data
- Mutation
- RNA, Messenger
- Tumor Cells, Cultured