Article
Predominant p53 mutations in enzootic bovine leukemic cell lines.
Veterinary immunology and immunopathology - 15 Jun 1996
Komori H, Ishiguro N, Horiuchi M, Shinagawa M, Aida Y
Abstract excerpt
The role of the p53 tumor suppressor gene in bovine lymphosarcomas, a fragment of about 100 bp corresponding to approximately 97% of the open reading frame of the p53 gene was first amplified from single-strand cDNA originated from calf thymus by polymerase chain reaction PCR) and sequenced to obtain the bovine wild-type p53 gene. At the amino acid level, the omologies of the bovine p53 gene with the human,...
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