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Article

Detection of p21ras mutations in colorectal adenomas and carcinomas by enzyme-linked immunosorbent assay.

Cancer - 15 Jul 1995

Schroy P C, Brown-Shimer S, Kim K, Johnson K A, Murnane M J, Yang S, O'Brien M J, Carney W P, Kupchik H Z

Abstract excerpt

BACKGROUND: Point mutations of the ras protooncogene, primarily within codons 12 and 13, are commonly identified in colorectal carcinomas and large adenomas. Despite data suggesting that ras genotyping may have clinical significance with respect to colorectal cancer screening and prognosis, more widespread use has been limited because of the lack of a suitable assay system. The principal objective of this study...

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PMID: 8625092
DOI: 10.1002/1097-0142(19950715)76:2<201::aid-cncr2820760207>3.0.co;2-t

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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