Article
ELISA-based Ki-ras gene mutation analyses in pancreatic and cholangiocarcinoma cells and tissues.
Oncology reports - 1 Jan 2000
Gabriel M, Henne-Bruns D, Kalthoff H
Abstract excerpt
Detection of Ki-ras mutations is one possible modality for diagnosis of human neoplasms, particularly of the gastrointestinal tract. Little is known about the protein expression levels of ras p21. Here we show a semi-quantitative analysis of mutated ras p21 in protein extracts from pancreatic and cholangiocarcinoma cell lines and from tumor tissues. Comparison with DNA sequencing data confirmed the specificity of...
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