Airway hyperresponsiveness to acetylcholine: segregation analysis and evidence for linkage to murine chromosome 6.

doi:10.1165/ajrcmb.14.5.8624254

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Article

Airway hyperresponsiveness to acetylcholine: segregation analysis and evidence for linkage to murine chromosome 6.

American journal of respiratory cell and molecular biology - 1 May 1996

Ewart S L, Mitzner W, DiSilvestre D A, Meyers D A, Levitt R C

Abstract excerpt

A genetic predisposition to nonspecific airway hyperresponsiveness (AHR) can be demonstrated in humans and in many animal models. The goal of the current study was to gain insight into the molecular mechanisms that determine AHR by mapping the genes that control this phenotype. We describe geneti...

Topics

Acetylcholine
Animals
Bronchial Hyperreactivity
Chromosome Mapping
Crosses, Genetic
DNA, Satellite
Female
Genetic Linkage
Genetic Markers
Genome
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mice

Mice, Inbred A

Mice, Inbred C3H

Models, Genetic

Phenotype

Source

Open in PubMed

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PMID: 8624254
DOI: 10.1165/ajrcmb.14.5.8624254

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8624254-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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