Article
Quantitative trait analysis of nickel-induced acute lung injury in mice.
American journal of respiratory cell and molecular biology - 1 Jun 2001
Prows D R, Leikauf G D
Abstract excerpt
The genetic determinants underlying susceptibility to acute lung injury have not been identified. Recently, we found that the strain distribution pattern for mean survival time (MST) to three irritants-ozone, ultrafine Teflon, and nickel sulfate- was shared between inbred mouse strains. For ozone-induced acute lung injury, survival was found to be a complex trait controlled by at least three quantitative trait...
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