Article
A conditional lethal mutant in the fission yeast 26 S protease subunit mts3+ is defective in metaphase to anaphase transition.
The Journal of biological chemistry - 8 Mar 1996
Gordon C, McGurk G, Wallace M, Hastie N D
Abstract excerpt
We have isolated a conditional lethal mutant mts3 in the fission yeast Schizosaccharomyces pombe which at the permissive temperature is resistant to the mitotic poison MBC and at the restrictive temperature is defective in metaphase to anaphase transition. The predicted amino acid sequence of mts...
Topics
- Amino Acid Sequence
- Anaphase
- Base Sequence
- Cell Cycle
- Cloning, Molecular
- DNA Primers
- DNA, Complementary
- Flow Cytometry
- Fungal Proteins
- Gene Library
- Genes, Fungal
- Genes, Lethal
- Kinetics
- Metaphase
- Molecular Sequence Data
- Mutation
- Peptide Hydrolases
- Phenotype