S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase.

doi:10.1038/366358a0

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Article

S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase.

Nature - 25 Nov 1993

Ghislain M, Udvardy A, Mann C

Abstract excerpt

We isolated two mutants from the yeast Saccharomyces cerevisiae, cim3-1 and cim5-1, that arrest cell division in G2/metaphase at 37 degrees C. CIM3 (identical to SUG1; ref. 1) and CIM5 are similar to each other and are members of a family of putative ATPases that have been proposed to be 26S prot...

Topics

Adenosine Triphosphatases
Amino Acid Sequence
CDC28 Protein Kinase, S cerevisiae
Cell Division
DNA-Binding Proteins
Endopeptidases
Fungal Proteins
G2 Phase
Metaphase
Molecular Sequence Data
Mutation
Proteasome Endopeptidase Complex
Repressor Proteins
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Sequence Homology, Amino Acid
Ubiquitins

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Identifiers

PMID: 8247132
DOI: 10.1038/366358a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8247132-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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