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Article

S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase.

Nature - 25 Nov 1993

Ghislain M, Udvardy A, Mann C

Abstract excerpt

We isolated two mutants from the yeast Saccharomyces cerevisiae, cim3-1 and cim5-1, that arrest cell division in G2/metaphase at 37 degrees C. CIM3 (identical to SUG1; ref. 1) and CIM5 are similar to each other and are members of a family of putative ATPases that have been proposed to be 26S protease subunits. We show here that CIM5 is the functional yeast homologue of the human MSS1 protein and that homologues...

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PMID: 8247132
DOI: 10.1038/366358a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase.PMID 8247132Read ↗

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The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae.Semantic proximity Read ↗

A novel yeast screen for mitotic arrest mutants identifies DOC1, a new gene involved in cyclin proteolysis.Semantic proximity Read ↗

A conditional lethal mutant in the fission yeast 26 S protease subunit mts3+ is defective in metaphase to anaphase transition.Semantic proximity Read ↗

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