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Article

The fission yeast genes pyp1+ and pyp2+ encode protein tyrosine phosphatases that negatively regulate mitosis.

Molecular and cellular biology - 1 Dec 1992

Ottilie S, Chernoff J, Hannig G, Hoffman C S, Erikson R L

Abstract excerpt

We have used degenerate oligonucleotide probes based on sequences conserved among known protein tyrosine phosphatases (PTPases) to identify two Schizosaccharomyces pombe genes encoding PTPases. We previously described the cloning of pyp1+ (S. Ottilie, J. Chernoff, G. Hannig, C. S. Hoffman, and R. L. Erikson, Proc. Natl. Acad. Sci. USA 88:3455-3459, 1991), and here we describe a second gene, called pyp2+. The C...

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Identifiers

PMID: 1448087
DOI: 10.1128/mcb.12.12.5571-5580.1992
PMCID: PMC360496

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