Article
Nin1p, a regulatory subunit of the 26S proteasome, is necessary for activation of Cdc28p kinase of Saccharomyces cerevisiae.
The EMBO journal - 3 Jul 1995
Kominami K, DeMartino G N, Moomaw C R, Slaughter C A, Shimbara N, Fujimuro M, Yokosawa H, Hisamatsu H, Tanahashi N, Shimizu Y
Abstract excerpt
The nin1-1 mutant of Saccharomyces cerevisiae cannot perform the G1/S and G2/M transitions at restrictive temperatures. At such temperatures, nin1-1 strains fail to activate histone H1 kinase after release from alpha factor-imposed G1 block and after release from hydroxyurea-imposed S block. The...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Biopolymers
- CDC28 Protein Kinase, S cerevisiae
- Cell Division
- Enzyme Activation
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genes, Lethal
- Humans
- Molecular Sequence Data
- Mutation