Article
The fission yeast dis3+ gene encodes a 110-kDa essential protein implicated in mitotic control.
Molecular and cellular biology - 1 Dec 1991
Kinoshita N, Goebl M, Yanagida M
Abstract excerpt
The fission yeast mutant dis3-54 is defective in mitosis and fails in chromosome disjunction. Its phenotype is similar to that of dis2-11, a mutant with a mutation in the type 1 protein phosphatase gene. We cloned the dis3+ gene by transformation. Nucleotide sequencing predicts a coding region of 970 amino acids interrupted by a 164-bp intron at the 65th codon. The predicted dis3+ protein shares a weak but...
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