Article
Human natural killer cell inhibitory receptors bind to HLA class I molecules.
European journal of immunology - 1 Feb 1996
Döhring C, Colonna M
Abstract excerpt
To obtain direct evidence that human natural killer cell (NK) inhibitory receptors physically interact with polymorphic determinants of major histocompatibility complex class I molecules, a receptor termed NK-associated transcript-2 has been produced as a soluble fusion protein with the human IgG1 Fc portion. This soluble receptor binds specifically to HLA-C alleles with serine 77 and asparagine 80 in cell...
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