Article
Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells.
The Journal of experimental medicine - 1 Sept 1995
Moretta A, Sivori S, Vitale M, Pende D, Morelli L, Augugliaro R, Bottino C, Moretta L
Abstract excerpt
The natural killer (NK) cell-specific p58 molecules EB6 and GL183 have been shown to represent the putative surface receptors for two distinct groups of human histocompatibility leukocyte antigen (HLA) C alleles. Interaction between p58 receptors and class I molecules expressed on target cells re...
Topics
- Alleles
- Antibodies, Monoclonal
- Calcium
- Cytotoxicity, Immunologic
- Glycosylation
- HLA-C Antigens
- Humans
- Killer Cells, Natural
- Lymphocyte Activation
- Molecular Weight
- Peptide Mapping
- Receptors, Immunologic
