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Article

Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor.

Immunity - 1 Jan 1996

Burshtyn D N, Scharenberg A M, Wagtmann N, Rajagopalan S, Berrada K, Yi T, Kinet J P, Long E O

Abstract excerpt

Cytolysis of target cells by natural killer (NK) cells and by some cytotoxic T cells occurs unless prevented by inhibitory receptors that recognize MHC class I on target cells. Human NK cells express a p58 inhibitory receptor specific for HLA-C. We report association of the tyrosine phosphatase HCP with the p58 receptor in NK cells. HCP association was dependent on tyrosine phosphorylation of p58. Phosphotyrosyl...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 8574854
DOI: 10.1016/s1074-7613(00)80300-3
PMCID: PMC2423819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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