Article
p49, a putative HLA class I-specific inhibitory NK receptor belonging to the immunoglobulin superfamily.
European journal of immunology - 1 Jun 1998
Cantoni C, Verdiani S, Falco M, Pessino A, Cilli M, Conte R, Pende D, Ponte M, Mikaelsson M S, Moretta L, Biassoni R
Abstract excerpt
NK cells display several killer inhibitory receptors (KIR) specific for different alleles of MHC class I molecules. A family of KIR are represented by type I transmembrane proteins belonging to the immunoglobulin superfamily (Ig-SF). Besides cDNA encoding for these KIR, additional cDNA have been...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- COS Cells
- Cell Membrane
- DNA, Complementary
- Histocompatibility Antigens Class I
- Humans
- Killer Cells, Natural
- Molecular Sequence Data
- Receptors, Immunologic
- Sequence Homology, Amino Acid