Six novel genes necessary for pre-mRNA splicing in Saccharomyces cerevisiae.

doi:10.1093/nar/24.6.1037

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Article

Six novel genes necessary for pre-mRNA splicing in Saccharomyces cerevisiae.

Nucleic acids research - 15 Mar 1996

Maddock J R, Roy J, Woolford J L

Abstract excerpt

We have identified six new genes whose products are necessary for the splicing of nuclear pre-mRNA in the yeast Saccharomyces cerevisiae. A collection of 426 temperature-sensitive yeast strains was generated by EMS mutagenesis. These mutants were screened for pre-mRNA splicing defects by an RNA g...

Topics

Alleles
Cell Nucleus
DEAD-box RNA Helicases
DNA Probes
Fungal Proteins
Genes, Fungal
Genes, Lethal
Genetic Complementation Test
Mutation
Phenotype
RNA Precursors
RNA Splicing
RNA, Fungal
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Spliceosomes
Temperature

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