Article
The PRP31 gene encodes a novel protein required for pre-mRNA splicing in Saccharomyces cerevisiae.
Nucleic acids research - 15 Mar 1996
Weidenhammer E M, Singh M, Ruiz-Noriega M, Woolford J L
Abstract excerpt
The pre-mRNA splicing factor Prp31p was identified in a screen of temperature-sensitive yeast strains for those exhibiting a splicing defect upon shift to the non- permissive temperature. The wild-type PRP31 gene was cloned and shown to be essential for cell viability. The PRP31 gene is predicted to encode a 60 kDa polypeptide. No similarities with other known splicing factors or motifs indicative of...
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