Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

U1 snRNA promotes the selection of nearby 5' splice sites by U6 snRNA in mammalian cells.

Genes & development - 1 Feb 1996

Hwang D Y, Cohen J B

Abstract excerpt

Communication between exon boundaries is a central feature of the exon definition model of pre-mRNA splice-site selection and an exon-bridging interaction involving U1 small nuclear RNA (snRNA) paired with the 5' splice site (5'ss) has been identified previously. It has become increasingly clear, however, that the 5'ss is not defined relative to the base-pairing interaction with U1, suggesting that a connection...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cell Line
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HeLa Cells

Share to Molecular Sequence Data

Share to Mutation

Share to RNA Splicing

Source

Identifiers

PMID: 8595884
DOI: 10.1101/gad.10.3.338

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

U1 snRNA promotes the selection of nearby 5' splice sites by U6 snRNA in mammalian cells.PMID 8595884Read ↗

Involvement of U6 snRNA in 5' splice site selection.Semantic proximity Read ↗

Mechanism for cryptic splice site activation during pre-mRNA splicing.Semantic proximity Read ↗

U5 snRNA interactions with exons ensure splicing precisionSemantic proximity Read ↗

Multiple roles for U6 snRNA in the splicing pathway.Semantic proximity Read ↗

Mutations in U6 snRNA that alter splice site specificity: implications for the active site.Semantic proximity Read ↗

Sequences upstream of the branch site are required to form helix II between U2 and U6 snRNA in a trans-splicing reaction.Semantic proximity Read ↗

The role of overlapping U1 and U11 5' splice site sequences in a negative regulator of splicing.Semantic proximity Read ↗

Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5'ss base pairing in yeast.Semantic proximity Read ↗

Base pairing with U6atac snRNA is required for 5' splice site activation of U12-dependent introns in vivo.Semantic proximity Read ↗

Randomization-selection analysis of snRNAs in vivo: evidence for a tertiary interaction in the spliceosome.Semantic proximity Read ↗

An intronic splicing enhancer binds U1 snRNPs to enhance splicing and select 5' splice sites.Semantic proximity Read ↗

Mutations in the conserved loop of human U5 snRNA generate use of novel cryptic 5' splice sites in vivo.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.