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Article

The role of overlapping U1 and U11 5' splice site sequences in a negative regulator of splicing.

RNA (New York, N.Y.) - 1 Mar 1999

Hibbert C S, Gontarek R R, Beemon K L

Abstract excerpt

Splicing of Rous sarcoma virus RNA is regulated in part by a cis-acting intronic RNA element called the negative regulator of splicing (NRS). An NRS mutant affecting nt 916-923 disrupts U11 snRNP binding and reduces NRS activity (Gontarek et al., 1993, Genes & Dev 7:1926-1936). However, we observed that a U15' splice site-like sequence, which overlapped the U11 site, was also disrupted by this mutation. To...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ribonucleoprotein, U1 Small Nuclear

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Source

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Identifiers

PMID: 10094303
DOI: 10.1017/s1355838299981347
PMCID: PMC1369763

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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