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Article

Evidence for the polymorphic oxidation of debrisoquine and proguanil in a Khmer (Cambodian) population.

British journal of clinical pharmacology - 1 Aug 1995

Wanwimolruk S, Thou M R, Woods D J

Abstract excerpt

The frequency distributions of the urinary metabolic ratios of debrisoquine and proguanil were measured in a population of unrelated Khmers. Out of 98 Khmer subjects studied, two were identified as poor metabolisers of debrisoquine when a metabolic ratio of 12.6 was used as the cut off point. This represents a prevalence of debrisoquine poor metabolisers of 2.1% (95% confidence interval 0.25-7.3%) which is...

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Identifiers

PMID: 8562301
DOI: 10.1111/j.1365-2125.1995.tb05772.x
PMCID: PMC1365178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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