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Article

Debrisoquine hydroxylation and sulfamethazine acetylation in a Chinese population.

Zhongguo yao li xue bao = Acta pharmacologica Sinica - 1 Sept 1990

Xu X M, Jiang W D

Abstract excerpt

Both debrisoquine hydroxylation and sulfamethazine acetylation phenotypes were studied in the same native Chinese population. Debrisoquine hydroxylation status was determined by HPLC assay of debrisoquine metabolic ratio in urine after a single oral dose of 10 mg debrisoquine. Three poor metabolizers were found in 220 subjects (1.36%). One hundred and one subjects of this population previously debrisoquine...

Topics

Acetylation
Adolescent
Adult
Asian People
China
Chromatography, High Pressure Liquid
Debrisoquin
Female
Humans
Hydroxylation
Male
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sulfamethazine

Source

Identifiers

PMID: 2130590

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2130590-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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