Evidence for the polymorphic oxidation of debrisoquine in the Thai population.

doi:10.1111/j.1365-2125.1990.tb03627.x

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Article

Evidence for the polymorphic oxidation of debrisoquine in the Thai population.

British journal of clinical pharmacology - 1 Feb 1990

Wanwimolruk S, Patamasucon P, Lee E J

Abstract excerpt

Debrisoquine polymorphism has been studied extensively in Caucasian populations. The prevalence of the poor metaboliser phenotype is 3-10% in European and American Caucasian populations but appears to be very low in Asian populations. This study was carried out to determine the metabolic oxidatio...

Topics

Adolescent
Adult
Debrisoquin
Female
Humans
Isoquinolines
Male
Middle Aged
Oxidation-Reduction
Phenotype
Polymorphism, Genetic
Sex Factors
Smoking
Thailand

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