Debrisoquine oxidation in an Italian population: a study in healthy subjects and in schizophrenic patients.

doi:10.1016/s1043-6618(05)80063-5

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Article

Debrisoquine oxidation in an Italian population: a study in healthy subjects and in schizophrenic patients.

Pharmacological research - 1 Jan 1992

Spina E, Campo G M, Calandra S, Caputi A P, Carrillo J A, Benitez J

Abstract excerpt

The debrisoquine oxidation phenotype was assessed in 137 healthy Italian volunteers and in 41 drug-free schizophrenic patients. A bimodal distribution of the urinary debrisoquine/4-hydroxydebrisoquine metabolic ratio was observed in healthy volunteers. Ten subjects were identified as poor metabol...

Topics

Adult
Chlorpromazine
Debrisoquin
Female
Humans
Italy
Male
Middle Aged
Oxidation-Reduction
Phenotype
Schizophrenia
White People

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