Article
Debrisoquine oxidation in an Italian population: a study in healthy subjects and in schizophrenic patients.
Pharmacological research - 1 Jan 1992
Spina E, Campo G M, Calandra S, Caputi A P, Carrillo J A, Benitez J
Abstract excerpt
The debrisoquine oxidation phenotype was assessed in 137 healthy Italian volunteers and in 41 drug-free schizophrenic patients. A bimodal distribution of the urinary debrisoquine/4-hydroxydebrisoquine metabolic ratio was observed in healthy volunteers. Ten subjects were identified as poor metabolizers, yielding a frequency of 7.3% which is similar to that reported in other European countries. The prevalence of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.