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Article

Polymorphic debrisoquin metabolism in a Turkish population.

Clinical pharmacology and therapeutics - 1 Apr 1994

Bozkurt A, Basci N E, Isimer A, Sayal A, Kayaalp S O

Abstract excerpt

Debrisoquin hydroxylation polymorphism was studied in 326 unrelated healthy Turkish volunteers. Debrisoquin sulfate (10 mg) was administered to subjects, and debrisoquin and 4-hydroxydebrisoquin were determined in the 0- to 8-hour urine samples. Debrisoquin oxidation was polymorphic, with 11 subjects (3.37%; 95% confidence interval, 1.69% to 6.07%) phenotyped as poor metabolizers. The metabolic ratio between...

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Source

Identifiers

PMID: 8162666
DOI: 10.1038/clpt.1994.48

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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