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Article

Suppression of platelet-derived growth factor alpha- and beta-receptor mRNA levels in human fibroblasts by SV40 T/t antigen.

Journal of cellular physiology - 1 Jan 1996

Wang J L, Nistér M, Bongcam-Rudloff E, Pontén J, Westermark B

Abstract excerpt

It is known that down-regulation of cell surface platelet-derived growth factor (PDGF) receptors accompanies transformation by SV40. In this work human embryonic lung fibroblasts were used as a model system to study the effects of SV 40 on PDGF receptor expression. It is shown that transformation by SV 40 early region leads to a total loss of PDGF alpha-receptor and partial loss of beta-receptor mRNA....

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Source

Identifiers

PMID: 8557760
DOI: 10.1002/(SICI)1097-4652(199601)166:1<12::AID-JCP2>3.0.CO;2-J

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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