Oct-1 POU domain-DNA interactions: cooperative binding of isolated subdomains and effects of covalent linkage.

doi:10.1101/gad.10.1.27

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Article

Oct-1 POU domain-DNA interactions: cooperative binding of isolated subdomains and effects of covalent linkage.

Genes & development - 1 Jan 1996

Klemm J D, Pabo C O

Abstract excerpt

Structural and biochemical studies of Oct-1 POU domain-DNA interactions have raised important questions about cooperativity and the role of the linker connecting the POU-specific domain and the POU homeo domain. To analyze these interactions, we have studied binding of the isolated domains. Surpr...

Topics

Base Sequence
Binding Sites
DNA Footprinting
DNA-Binding Proteins
Deoxyribonuclease I
Genes, Homeobox
Homeodomain Proteins
Host Cell Factor C1
Models, Molecular
Molecular Sequence Data
Mutation
Octamer Transcription Factor-1
Peptide Fragments
Thermodynamics
Transcription Factors

Source

Open in PubMed

Identifiers

PMID: 8557192
DOI: 10.1101/gad.10.1.27

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8557192-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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