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Article

Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers.

Genes & development - 15 Aug 2003

Reményi Attila, Lins Katharina, Nissen L Johan, Reinbold Rolland, Schöler Hans R, Wilmanns Matthias

Abstract excerpt

Members of the POU and SOX transcription factor families exemplify the partnerships established between various transcriptional regulators during early embryonic development. Although functional cooperativity between key regulator proteins is pivotal for milestone decisions in mammalian development, little is known about the underlying molecular mechanisms. In this study, we focus on two transcription factors,...

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Share to Chromosomal Proteins, Non-Histone
Share to Enhancer Elements, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fibroblast Growth Factors

Share to High Mobility Group Proteins

Share to HMGB Proteins

Share to Octamer Transcription Factor-3

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Source

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Identifiers

PMID: 12923055
DOI: 10.1101/gad.269303
PMCID: PMC196258

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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