Article
Drosophila MAP kinase kinase suppresses the vulvaless phenotype of lin-3, let-23 and lin-45 mutations in Caenorhabditis elegans.
Mechanisms of development - 1 Sept 1995
Koga M, Ohshima Y
Abstract excerpt
The vulva of the nematode Caenorhabditis elegans develops from the three vulval precursor cells (VPCs) that are induced by a signal from the gonadal anchor cell. This signal is thought to be mediated by a receptor tyrosine kinase (RTK) in the VPCs to a downstream signal transduction pathway. A mitogen-activated protein kinase kinase (MAPKK) has been found to be one of the major components of an RTK pathway in...
Topics
- Animals
- Base Sequence
- Caenorhabditis elegans
- Drosophila
- Drosophila Proteins
- Female
- Genotype
- Molecular Sequence Data
- Mutation
- Phenotype
- Protein Kinases
- Signal Transduction