Article
Multiple functions of let-23, a Caenorhabditis elegans receptor tyrosine kinase gene required for vulval induction.
Genetics - 1 Jun 1991
Aroian R V, Sternberg P W
Abstract excerpt
The let-23 gene, which encodes a putative tyrosine kinase of the epidermal growth factor (EGF) receptor subfamily, has multiple functions during Caenorhabditis elegans development. We show that let-23 function is required for vulval precursor cells (VPCs) to respond to the signal that induces vul...
Topics
- Alleles
- Animals
- Caenorhabditis
- Cell Differentiation
- ErbB Receptors
- Female
- Genetic Complementation Test
- Mutation
- Organ Specificity
- Phenotype
- Protein-Tyrosine Kinases
- Vulva