Article
Inhibition of Caenorhabditis elegans vulval induction by gap-1 and by let-23 receptor tyrosine kinase.
Genes & development - 15 Oct 1997
Hajnal A, Whitfield C W, Kim S K
Abstract excerpt
During induction of the Caenorhabditis elegans hermaphrodite vulva, a signal from the anchor cell activates the LET-23 epidermal growth factor receptor (EGFR)/LET-60 Ras/MPK-1 MAP kinase signaling pathway in the vulval precursor cells. We have characterized two mechanisms that limit the extent of...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Calcium-Calmodulin-Dependent Protein Kinases
- Drosophila
- Embryo, Nonmammalian
- Embryonic Induction
- ErbB Receptors
- Female
- Genes, Helminth
- Helminth Proteins
- Humans
- Mitogen-Activated Protein Kinase 1
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction