Article
sur-2, a novel gene, functions late in the let-60 ras-mediated signaling pathway during Caenorhabditis elegans vulval induction.
Genes & development - 15 Sept 1995
Singh N, Han M
Abstract excerpt
We describe here a new gene acting downstream of let-60 ras in the vulval signaling pathway of Caenorhabditis elegans. The sur-2 (suppressor of ras) gene is defined by eight mutations identified in a genetic screen for suppressors of the Multivulva phenotype of let-60(n1046), an activated let-60...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Embryonic Induction
- Exons
- Female
- Gene Expression Regulation, Developmental
- Genes, Helminth
- Helminth Proteins
- Introns
- Models, Biological
- Molecular Sequence Data
- Mutation
- Restriction Mapping
- Signal Transduction
- Suppression, Genetic