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Article

A lin-45 raf enhancer screen identifies eor-1, eor-2 and unusual alleles of Ras pathway genes in Caenorhabditis elegans.

Genetics - 1 May 2002

Rocheleau Christian E, Howard Robyn M, Goldman Alissa P, Volk Mandy L, Girard Laura J, Sundaram Meera V

Abstract excerpt

In Caenorhabditis elegans, the Ras/Raf/MEK/ERK signal transduction pathway controls multiple processes including excretory system development, P12 fate specification, and vulval cell fate specification. To identify positive regulators of Ras signaling, we conducted a genetic screen for mutations that enhance the excretory system and egg-laying defects of hypomorphic lin-45 raf mutants. This screen identified...

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Identifiers

PMID: 12019228
DOI: 10.1093/genetics/161.1.121
PMCID: PMC1462089

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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