Article
Autoprocessing: an essential step for the activation of HIV-1 protease.
The Biochemical journal - 1 Jun 1996
Wan M, Takagi M, Loh B N, Xu X Z, Imanaka T
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) expresses its structural and functional proteins within Gag-Pol precursor polyproteins. Specific proteolytic processing of the precursors by the viral protease is critical for the maturation and infectivity of viral particles. To observe the influence o...
Topics
- Base Sequence
- Binding Sites
- Blotting, Western
- DNA Primers
- Enzyme Activation
- Escherichia coli
- HIV Protease
- HIV-1
- Molecular Sequence Data
- Mutation
- Peptides
- Protein Precursors
- Protein Processing, Post-Translational