Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spleen necrosis virus gag polyprotein is necessary for particle assembly and release but not for proteolytic processing.

Journal of virology - 1 Jun 1990

Weaver T A, Talbot K J, Panganiban A T

Abstract excerpt

The nature of spleen necrosis virus pol gene expression and the role of gag and gag-pol polyproteins in virion assembly was investigated. The DNA sequence of the gag-pol junction revealed that the two genes occupy the same open reading frame but are separated by an in-frame amber stop codon. Biochemical analysis of gag-pol translational readthrough in vitro and in Escherichia coli suggests that, in a manner...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Cell Line

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cloning, Molecular

Share to Escherichia coli

Share to Molecular Sequence Data

Share to Mutation

Share to Plasmids

Source

Open in PubMed Open full text

Identifiers

PMID: 2186174
DOI: 10.1128/JVI.64.6.2642-2652.1990
PMCID: PMC249442

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Spleen necrosis virus gag polyprotein is necessary for particle assembly and release but not for proteolytic processing.PMID 2186174Read ↗

Extensive regions of pol are required for efficient human immunodeficiency virus polyprotein processing and particle maturation.Semantic proximity Read ↗

HIV Gag polyprotein: processing and early viral particle assemblySemantic proximity Read ↗

Sequence analysis of infectious pancreatic necrosis virus genome segment B and its encoded VP1 protein: A putative RNA-dependent RNA polymerase lacking the Gly-Asp-Asp motifSemantic proximity Read ↗

N myristoylation of the spleen necrosis virus matrix protein is required for correct association of the Gag polyprotein with intracellular membranes and for particle formation.Semantic proximity Read ↗

Avian sarcoma leukemia virus protease linked to the adjacent Gag polyprotein is enzymatically active.Semantic proximity Read ↗

Processing of avian retroviral gag polyprotein precursors is blocked by a mutation at the NC-PR cleavage site.Semantic proximity Read ↗

Assembly and maturation of the bacteriophage lambda procapsid: gpC is the viral protease.Semantic proximity Read ↗

Overexpression of the HIV-1 Gag-Pol Polyprotein Results in Intracellular Activation of HIV-1 Protease and Inhibition of Assembly and Budding of Virus-like ParticlesSemantic proximity Read ↗

Recovery of infectious murine norovirus using pol II-driven expression of full-length cDNASemantic proximity Read ↗

The spacer peptide between human immunodeficiency virus capsid and nucleocapsid proteins is essential for ordered assembly and viral infectivity.Semantic proximity Read ↗

trans-acting proteins involved in RNA encapsidation and viral assembly in human immunodeficiency virus type 1.Semantic proximity Read ↗

Reverse transcriptase and protease activities of avian leukosis virus Gag-Pol fusion proteins expressed in insect cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.