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Article

In vivo assay of p53 function in homologous recombination between simian virus 40 chromosomes.

Journal of virology - 1 Feb 1996

Wiesmüller L, Cammenga J, Deppert W W

Abstract excerpt

To investigate a possible role of p53 in DNA exchange mechanisms, we have developed a model system which allows us to quantify homologous recombination rates in eukaryotic cells. We generated two types of simian virus 40 (SV40) whose genomes were mutated in such a way that upon double infection of monkey cells, virus particles can be released only after interchromosomal exchange of genetic material. This test...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 8551610
DOI: 10.1128/JVI.70.2.737-744.1996
PMCID: PMC189874

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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