Article
Simian virus 40 mutants with amino-acid substitutions near the amino terminus of large T antigen.
Virus genes - 1 Apr 1992
Peden K W, Pipas J M
Abstract excerpt
A series of amino-acid substitution mutants has been made with changes in the region of simian virus 40 large tumor antigen (T antigen) that is shared with the small tumor antigen (t antigen). Both single and multiple amino-acid replacements were obtained using the heteroduplex deletion loop method and sodium bisulfite as the mutagen. The mutants could be divided into five phenotypic classes on the basis of their...
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