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Article

Interaction of simian virus 40 large T-antigen with cellular DNA polymerase alpha: studies with various T-antigen mutants of SV40.

Archives of virology - 1 Jan 1991

Pistillo J M, Vishwanatha J K

Abstract excerpt

Simian virus 40 (SV40) large T antigen binds to host cell DNA polymerase alpha and the T-antigen-DNA polymerase alpha complex is implicated in the initiation of viral DNA replication. We have examined various SV40 T-antigen mutants to test the correspondence between viral DNA replication and T-antigen-DNA polymerase alpha complex formation. The various SV40 T-antigen mutants were used to either infect or...

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Identifiers

PMID: 1646591
DOI: 10.1007/BF01311307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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