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Article

Stable T-p53 complexes are not required for replication of simian virus 40 in culture or for enhanced phosphorylation of T antigen and p53.

Journal of virology - 1 Apr 1991

Lin J Y, Simmons D T

Abstract excerpt

We generated a number of simian virus 40 (SV40) mutants with single amino acid substitutions in T antigen between residues 388 and 411. All but one mutant (398LV) replicated like wild-type SV40 and gave rise to normal-size plaques. Three different mutations at residue 402 (Asp to Glu, Asn, or His) totally prevented the formation of stable complexes with the cellular protein p53 in monkey cells but had no effect...

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Identifiers

PMID: 1705996
DOI: 10.1128/JVI.65.4.2066-2072.1991
PMCID: PMC240060

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Stable T-p53 complexes are not required for replication of simian virus 40 in culture or for enhanced phosphorylation of T antigen and p53.PMID 1705996Read ↗

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