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Article

A novel host cell reactivation assay to assess homologous recombination capacity in human cancer cell lines.

Biochemical and biophysical research communications - 16 Feb 2001

Slebos R J, Taylor J A

Abstract excerpt

Repair of DNA double-strand breaks (DSB) is essential for cell viability and genome stability. Homologous recombination repair plays an important role in DSB repair and impairment of this repair mechanism may lead to loss of genomic integrity, which is one of the hallmarks of cancer. Recent resea...

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Identifiers

PMID: 11178982
DOI: 10.1006/bbrc.2001.4335

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11178982-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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