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Article

Intrachromosomal recombination mediated by papovavirus large T antigens.

Journal of virology - 1 Jun 1990

St-Onge L, Bouchard L, Laurent S, Bastin M

Abstract excerpt

To investigate the mechanism by which the large T antigen (T-Ag) of polyomavirus and simian virus 40 can promote recombination in mammalian cells, we analyzed homologous recombination events occurring between two defective copies of the polyomavirus middle T (pmt) oncogene lying in close proximity on the same chromosome in a rat cell line. Reconstitution of a functional pmt gene by spontaneous recombination...

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Identifiers

PMID: 2159556
DOI: 10.1128/JVI.64.6.2958-2966.1990
PMCID: PMC249480

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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