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Article

Analysis of the growth and transformation suppressor domains of promyelocytic leukemia gene, PML.

The Journal of biological chemistry - 5 Jan 1996

Le X F, Yang P, Chang K S

Abstract excerpt

The promyelocytic leukemia gene (PML) involved in the t(15;17) (q22;q12) translocation in acute promyelocytic leukemia is a growth suppressor. To elucidate the functional domains of PML, several mutants lacking the nuclear localization signal (PMLnls-), the dimerization domain (PMLdim-), the proline-rich domain at the N-terminal (PMLpro-), the proline-rich RING finger motif (PMLpr-), the proline-rich RING finger...

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Source

Identifiers

PMID: 8550548
DOI: 10.1074/jbc.271.1.130

Genes

PML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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