Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Subcellular distribution of nuclear import-defective isoforms of the promyelocytic leukemia protein.

BMC molecular biology - 21 Nov 2010

Jul-Larsen Asne, Grudic Amra, Bjerkvig Rolf, Bøe Stig O

Abstract excerpt

BACKGROUND: The promyelocytic leukemia (PML) protein participates in a number of cellular processes, including transcription regulation, apoptosis, differentiation, virus defense and genome maintenance. This protein is structurally organized into a tripartite motif (TRIM) at its N-terminus, a nuc...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Active Transport, Cell Nucleus
Share to Cytoplasm
Share to Endosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lysosomes

Share to Nuclear Envelope

Share to Promyelocytic Leukemia Protein

Share to Protein Isoforms

Share to Tumor Suppressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 21092142
DOI: 10.1186/1471-2199-11-89
PMCID: PMC2998510

Genes

PML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21092142-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Subcellular distribution of nuclear import-defective isoforms of the promyelocytic leukemia protein.PMID 21092142Read ↗

The function, regulation and therapeutic implications of the tumor suppressor protein, PMLSemantic proximity Read ↗

PML nuclear bodies: regulation, function and therapeutic perspectivesSemantic proximity Read ↗

Characterization of Endogenous Human Promyelocytic Leukemia IsoformsSemantic proximity Read ↗

PML: Regulation and multifaceted function beyond tumor suppressionSemantic proximity Read ↗

The PML hub: An emerging actor of leukemia therapiesSemantic proximity Read ↗

Selective inhibition of the NLRP3 inflammasome by targeting to promyelocytic leukemia protein in mouse and humanSemantic proximity Read ↗

Intranuclear trafficking of transcription factors: implications for biological control.Semantic proximity Read ↗

Regulation of p53 activity in nuclear bodies by a specific PML isoformSemantic proximity Read ↗

The functional roles of PML nuclear bodies in genome maintenanceSemantic proximity Read ↗

Requirement of PML SUMO interacting motif for RNF4- or arsenic trioxide-induced degradation of nuclear PML isoforms.Semantic proximity Read ↗

Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation.Semantic proximity Read ↗

Progressive multifocal leukoencephalopathy and promyelocytic leukemia nuclear bodies: a review of clinical, neuropathological, and virological aspects of JC virus-induced demyelinating diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.