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Article

Modulation of E-cadherin localization in cells expressing wild-type E1A 12S or hypertransforming mutants.

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Aug 1995

Gopalakrishnan S, Quinlan M P

Abstract excerpt

The adenovirus E1A 12S gene can immortalize primary epithelial cells such that they retain expression of epithelial cell characteristics. E1A 12S can also cooperate with an activated ras oncogene to cause tumorigenic transformation of primary cells. Specific substitution and deletion mutants of E1A 12S cooperate more efficiently with ras to produce foci with a hypertransformed phenotype, wherein the cells are...

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PMID: 8547227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Modulation of E-cadherin localization in cells expressing wild-type E1A 12S or hypertransforming mutants.PMID 8547227Read ↗

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