Article
Linkage study of the D5 dopamine receptor gene (DRD5) in multiplex Icelandic and English schizophrenia pedigrees.
The American journal of psychiatry - 1 Jan 1996
Kalsi G, Sherrington R, Mankoo B S, Brynjolfsson J, Sigmundsson T, Curtis D, Read T, Murphy P, Butler R, Petursson H, Gurling H M
Abstract excerpt
OBJECTIVE: The authors investigated the possibility that genetic variation or mutation of the dopamine D5 receptor gene might modify susceptibility to schizophrenia. METHOD: Twenty-three Icelandic and English pedigrees containing multiple cases of schizophrenia were genotyped by using a highly informative microsatellite for the D5 dopamine receptor gene DRD5. RESULTS: By means of three different affection models,...
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