Article
Association between schizophrenia and a microsatellite polymorphism at the dopamine D5 receptor gene.
Psychiatric genetics - 1 Jan 1997
Williams N M, Cardno A G, Murphy K C, Jones L A, Asherson P, McGuffin P, Owen M J
Abstract excerpt
An association study of 97 patients with DSM-III-R schizophrenia and 97 matched controls was performed using a polymorphic microsatellite repeat at the dopamine D5 receptor gene. We observed a significant difference between the allele frequencies of patients and controls (chi 2 = 23.4, df = 12, p...
Topics
- Alleles
- DNA
- Gene Frequency
- Humans
- Microsatellite Repeats
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Receptors, Dopamine D1
- Receptors, Dopamine D5
- Reference Values
- Schizophrenia