Article
New DNA markers with increased informativeness show diminished support for a chromosome 5q11-13 schizophrenia susceptibility locus and exclude linkage in two new cohorts of British and Icelandic families.
Annals of human genetics - 1 May 1999
Kalsi G, Mankoo B, Curtis D, Sherrington R, Melmer G, Brynjolfsson J, Sigmundsson T, Read T, Murphy P, Petursson H, Gurling H
Abstract excerpt
Genetic linkage of schizophrenia to markers at 5q11.2-13.3 had been reported previously in five Icelandic and two British families, but attempts at replication in independent samples have been unsuccessful. We report here an update on the diagnoses and results of linkage analyses using newer highly polymorphic microsatellite markers at or near the loci D5S76 and D5S39 in the original sample of pedigrees and in...
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