Article
The clonogenic precursor cell in multiple myeloma.
Leukemia & lymphoma - 1 Jul 1995
Bakkus M H, Van Riet I, De Greef C, Van Camp B, Thielemans K
Abstract excerpt
Multiple myeloma is characterized by the monoclonal expansion of plasma cells in the bone marrow. Although the predominant cell type is the plasma cell, the initial oncogenic transformation is considered to take place in a more immature B cell. There is still much controversy about this precursor cell type. Phenotypic analysis of bone marrow and peripheral blood revealed that in multiple myeloma a great diversity...
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