Article
Myeloma stem cell phenotype. Implications for treatment.
Hematology/oncology clinics of North America - 1 Feb 1997
Epstein J
Abstract excerpt
The phenotypic heterogeneity of myeloma cells in fact delineates a differentiation process that appears to be an integral part of the disease process. Immature myeloma cells interact with their microenvironment differently than do the more mature cells. As a result of this interaction, the immature cells display different responses to chemotherapy than do the mature cells. Addressing this issue by tailoring...
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